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KMID : 1143420220150472873
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Public Health Weekly Report
2022 Volume.15 No. 47 p.2873 ~ p.2895
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Severity of COVID-19 Associated with SARS-CoV-2 Variants Circulating in the Republic of Korea
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Ryu Bo-Yeong
Shin Eun-Jeong
Kim Na-Young
Kim Dong-Hwi
Lee Hyun-Ju
Kim Ah-Ra
Park Shin-Young
Ahn Seon-Hee
Jang Jin-Hwa
Kim Seong-Sun
Kwon Dong-Hyok
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Abstract
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We aimed to identify the severity of the Coronavirus disease 2019 specifically according to the SARS-CoV-2 variant in
the Republic of Korea by describing the number of severe/critical cases and deaths, case severity rate (CSR) and case fatality rate (CFR). A total of 23,496,849 confirmed cases were reported during January 20, 2020 to September 3, 2022. 26,472
(0.11%) cases were considered severe/critical and 27,471 (0.12%) resulted in death. The omicron BA.1/BA.2 period showed most severe/critical cases and deaths accounting for 40.7% (10,772 patients) and 66.4% (18,252 patients), respectively. In the omicron variant dominant period, the proportion of the age 80 and over saw on increase in severe/critical cases and deaths by 26.4%p, 7.4%p, respectively, than those in the delta dominant period. The CSR and CFR were 0.20% and 0.12% over that period. The CSR decreased from 2.98% in the pre-delta dominant period to 2.14% in the delta dominant period, and 0.14% in the omicron BA.1/BA.2 period. CFR was also highest at 1.15% in the pre-delta dominant period and decreased to 0.95% in the delta dominant period, 0.10% in the omicron BA.1/BA.2 period. Despite the increase in severity of the delta variant, overall severity decreased in the delta dominant period showing continuous decrease in the omicron dominant period. In the omicron dominant period, the proportion of the elderly of severe/critical and fatal condition increased which suggests the importance of focusing on the response strategy of the elderly.
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KEYWORD
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COVID-19, SARS-CoV-2, COVID-19 severity, COVID-19 variants, COVID-19 deaths
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